TIMP1 Rabbit pAb
Cat No.: APA5057
Size：
| Product Name: | TIMP1 Rabbit pAb |
| Cat No.: | APA5057 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human TIMP1 |
| calculated molecular weight: | 23 kDa |
| observed molecular weight: | 26 kDa |
| genbank accession number: | P01033 |
| gene id (ncbi): | 7076 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | EPA; EPO; HCI; CLGI; TIMP; TIMP-1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008] |