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IRS2 Rabbit pAb

Cat No.: APA5055
Size:
Product Name: IRS2 Rabbit pAb
Cat No.: APA5055
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,IP
clonality: Polyclonal
recommended dilution: WB: 1:5000
IHC: 1:20
ICC/IF: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human IRS2
calculated molecular weight: 137 kDa
observed molecular weight: 185 kDa
genbank accession number: Q9Y4H2
gene id (ncbi): 8660
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: IRS-2
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008]