Fascin Rabbit pAb
Cat No.: APA5052
Size：
| Product Name: | Fascin Rabbit pAb |
| Cat No.: | APA5052 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000-1:10000 IHC: 1:50-1:200 ICC/IF: 1:50 FC: 1:20-1:100 IP: 1:20-1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Fascin |
| calculated molecular weight: | 54 kDa |
| observed molecular weight: | 54 kDa |
| genbank accession number: | Q16658 |
| gene id (ncbi): | 6624 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HSN; SNL; p55; FAN1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin--s lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011] |