Oct-4 Rabbit pAb
Cat No.: APA5039
Size：
| Product Name: | Oct-4 Rabbit pAb |
| Cat No.: | APA5039 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB,IHC,ICC/IF,FC,IP,ChIP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20-1:500 ICC/IF: 1:50 FC: 1:50 IP: 1:20 ChIP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Oct4 |
| calculated molecular weight: | 39 kDa |
| observed molecular weight: | 45 kDa |
| genbank accession number: | Q01860 |
| gene id (ncbi): | 5460 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing--s sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013] |