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Rho A/B/C Rabbit pAb

Cat No.: APA5033
Size:
Product Name: Rho A/B/C Rabbit pAb
Cat No.: APA5033
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:500
ICC/IF: 1:100
FC: 1:50
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Rho C
calculated molecular weight: 22 kDa
observed molecular weight: 22 kDa
genbank accession number: P08134
gene id (ncbi): 389
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: H9; ARH9; ARHC; RHOH9
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]