COPS8 Rabbit pAb
Cat No.: APA5024
Size:
Product Name: | COPS8 Rabbit pAb |
Cat No.: | APA5024 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50 IP: 1:20-1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human COPS8 |
calculated molecular weight: | 23 kDa |
observed molecular weight: | 23 kDa |
genbank accession number: | Q99627 |
gene id (ncbi): | 10920 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | COP9; CSN8; SGN8 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |