MYSM1 Rabbit pAb
Cat No.: APA5014
Size：
| Product Name: | MYSM1 Rabbit pAb |
| Cat No.: | APA5014 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human MYSM1 |
| calculated molecular weight: | 95 kDa |
| observed molecular weight: | 96,55 kDa |
| genbank accession number: | Q5VVJ2 |
| gene id (ncbi): | 114803 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | 2ADUB; 2A-DUB |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. |