MYBPC3 Rabbit pAb
Cat No.: APA5007
Size:
Product Name: | MYBPC3 Rabbit pAb |
Cat No.: | APA5007 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human MYBPC3 |
calculated molecular weight: | 141 kDa |
observed molecular weight: | 150 kDa |
genbank accession number: | Q14896 |
gene id (ncbi): | 4607 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | FHC; CMH4; CMD1MM; LVNC10; MYBP-C |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008] |