alpha 1 Spectrin Rabbit pAb
Cat No.: APA4994
Size:
Product Name: | alpha 1 Spectrin Rabbit pAb |
Cat No.: | APA4994 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20-1:50 FC: 1:20-1:100 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human alpha 1 Spectrin |
calculated molecular weight: | 280 kDa |
observed molecular weight: | 280 kDa |
genbank accession number: | P02549 |
gene id (ncbi): | 6708 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | EL2; HPP; HS3; SPH3; SPTA |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3. [provided by RefSeq, Aug 2017] |