Somatostatin Receptor 5 Rabbit pAb
Cat No.: APA4987
Size:
Product Name: | Somatostatin Receptor 5 Rabbit pAb |
Cat No.: | APA4987 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Somatostatin Receptor 5 |
calculated molecular weight: | 39 kDa |
observed molecular weight: | 54-63 kDa |
genbank accession number: | P35346 |
gene id (ncbi): | 6755 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | SS-5-R |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010] |