Neurofascin Rabbit pAb
Cat No.: APA4982
Size：
| Product Name: | Neurofascin Rabbit pAb |
| Cat No.: | APA4982 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:500 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse Neurofascin |
| calculated molecular weight: | 150 kDa |
| observed molecular weight: | 186,155,75 kDa |
| genbank accession number: | Q810U3 |
| gene id (ncbi): | 269116 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | NF; AA387016; mKIAA0756; D430023G06Rik |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined. [provided by RefSeq, May 2009] |