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Plakophilin 1 Rabbit pAb

Cat No.: APA4961
Size:
Product Name: Plakophilin 1 Rabbit pAb
Cat No.: APA4961
source: Rabbit
reactivity: Human, Mouse
applications: WB,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
ICC/IF: 1:20
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Plakophilin 1
calculated molecular weight: 81 kDa
observed molecular weight: 81 kDa
genbank accession number: Q13835
gene id (ncbi): 5317
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: B6P
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]