Plakophilin 1 Rabbit pAb
Cat No.: APA4961
Size:
Product Name: | Plakophilin 1 Rabbit pAb |
Cat No.: | APA4961 |
source: | Rabbit |
reactivity: | Human, Mouse |
applications: | WB,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Plakophilin 1 |
calculated molecular weight: | 81 kDa |
observed molecular weight: | 81 kDa |
genbank accession number: | Q13835 |
gene id (ncbi): | 5317 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | B6P |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |