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GBA Rabbit pAb

Cat No.: APA4932
Size:
Product Name: GBA Rabbit pAb
Cat No.: APA4932
source: Rabbit
reactivity: Human, Rat
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:20-1:100
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human GBA
calculated molecular weight: 60 kDa
observed molecular weight: 60 kDa
genbank accession number: P04062
gene id (ncbi): 2629
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: GCB; GBA1; GLUC
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]