Dnmt1 Rabbit pAb
Cat No.: APA4931
Size：
| Product Name: | Dnmt1 Rabbit pAb |
| Cat No.: | APA4931 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20-1:500 ICC/IF: 1:200 FC: 1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Dnmt1 |
| calculated molecular weight: | 183 kDa |
| observed molecular weight: | 183 kDa |
| genbank accession number: | P26358 |
| gene id (ncbi): | 1786 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; m.HsaI |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |