RNA polymerase II RPB1 Rabbit pAb
Cat No.: APA4928
Size：
| Product Name: | RNA polymerase II RPB1 Rabbit pAb |
| Cat No.: | APA4928 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,ICC/IF,FC,ChIP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:20-1:100 ChIP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human RNA polymerase II RPB1 |
| calculated molecular weight: | 217 kDa |
| observed molecular weight: | 250 kDa |
| genbank accession number: | P24928 |
| gene id (ncbi): | 5430 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; RpIILS; hsRPB1; hRPB220 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008] |