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S100 alpha Rabbit pAb

Cat No.: APA4927
Size:
Product Name: S100 alpha Rabbit pAb
Cat No.: APA4927
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:20-1:100
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human S100 alpha
calculated molecular weight: 11 kDa
observed molecular weight: 11 kDa
genbank accession number: P23297
gene id (ncbi): 6271
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: S100; S100A; S100-alpha
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]