Langerin Rabbit pAb
Cat No.: APA4925
Size：
| Product Name: | Langerin Rabbit pAb |
| Cat No.: | APA4925 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | IHC |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Langerin |
| calculated molecular weight: | 37 kDa |
| observed molecular weight: | |
| genbank accession number: | Q9UJ71 |
| gene id (ncbi): | 50489 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CLEC4K |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010] |