CD11b Rabbit pAb
Cat No.: APA4913
Size：
| Product Name: | CD11b Rabbit pAb |
| Cat No.: | APA4913 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human CD11b |
| calculated molecular weight: | 127 kDa |
| observed molecular weight: | 170 kDa |
| genbank accession number: | P11215 |
| gene id (ncbi): | 3684 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (--Mac-1--), or inactivated-C3b (iC3b) receptor 3 (--CR3--). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |