Cytokeratin 13 Rabbit pAb
Cat No.: APA4908
Size:
Product Name: | Cytokeratin 13 Rabbit pAb |
Cat No.: | APA4908 |
source: | Rabbit |
reactivity: | Human, Mouse |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:5000-1:20000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Cytokeratin 13 |
calculated molecular weight: | 50 kDa |
observed molecular weight: | 50 kDa |
genbank accession number: | P13646 |
gene id (ncbi): | 3860 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | K13; CK13; WSN2 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008] |