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TMEM16A Rabbit pAb

Cat No.: APA4902
Size:
Product Name: TMEM16A Rabbit pAb
Cat No.: APA4902
source: Rabbit
reactivity: Human
applications: IHC,FC
clonality: Polyclonal
recommended dilution: IHC: 1:20-1:500
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human TMEM16A
calculated molecular weight: 114 kDa
observed molecular weight:
genbank accession number: Q5XXA6
gene id (ncbi): 55107
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: DOG1; TAOS2; ORAOV2; TMEM16A
category: Primary Ab
concentration: 0.5mg/ml
background: Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.