Upa Rabbit pAb
Cat No.: APA4868
Size：
| Product Name: | Upa Rabbit pAb |
| Cat No.: | APA4868 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:2000 ICC/IF: 1:20-1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Upa |
| calculated molecular weight: | 49 kDa |
| observed molecular weight: | 49 kDa |
| genbank accession number: | P00749 |
| gene id (ncbi): | 5328 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ATF; QPD; UPA; URK; u-PA; BDPLT5 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer--s disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |