Desmoglein 3 Rabbit pAb
Cat No.: APA4844
Size:
Product Name: | Desmoglein 3 Rabbit pAb |
Cat No.: | APA4844 |
source: | Rabbit |
reactivity: | Human |
applications: | IHC |
clonality: | Polyclonal |
recommended dilution: | IHC: 1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human Desmoglein 3 |
calculated molecular weight: | 108 kDa |
observed molecular weight: | |
genbank accession number: | P32926 |
gene id (ncbi): | 1830 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | PVA; CDHF6 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016] |