NMDAR2B Rabbit pAb
Cat No.: APA4842
Size：
| Product Name: | NMDAR2B Rabbit pAb |
| Cat No.: | APA4842 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of mouse NMDAR2B |
| calculated molecular weight: | 166 kDa |
| observed molecular weight: | 166 kDa |
| genbank accession number: | Q01097 |
| gene id (ncbi): | 14812 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | NR2B; GluN2B; Nmdar2b; AW490526 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. |