MyD88 Rabbit pAb
Cat No.: APA4802
Size:
Product Name: | MyD88 Rabbit pAb |
Cat No.: | APA4802 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000 IHC: 1:20 ICC/IF: 1:50 FC: 1:100 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human MyD88 |
calculated molecular weight: | 33 kDa |
observed molecular weight: | 33 kDa |
genbank accession number: | Q99836 |
gene id (ncbi): | 4615 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | MYD88D |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] |