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MyD88 Rabbit pAb

Cat No.: APA4802
Size:
Product Name: MyD88 Rabbit pAb
Cat No.: APA4802
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:2000
IHC: 1:20
ICC/IF: 1:50
FC: 1:100
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human MyD88
calculated molecular weight: 33 kDa
observed molecular weight: 33 kDa
genbank accession number: Q99836
gene id (ncbi): 4615
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: MYD88D
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]