p57 Kip2 Rabbit pAb
Cat No.: APA4799
Size：
| Product Name: | p57 Kip2 Rabbit pAb |
| Cat No.: | APA4799 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human p57 Kip2 |
| calculated molecular weight: | 32 kDa |
| observed molecular weight: | 57 kDa |
| genbank accession number: | P49918 |
| gene id (ncbi): | 1028 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | BWS; WBS; p57; BWCR; KIP2; p57Kip2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |