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IKZF3 Rabbit pAb

Cat No.: APA4786
Size:
Product Name: IKZF3 Rabbit pAb
Cat No.: APA4786
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:2000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human IKZF3
calculated molecular weight: 58 kDa
observed molecular weight: 58 kDa
genbank accession number: Q9UKT9
gene id (ncbi): 22806
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AIO; AIOLOS; ZNFN1A3
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]