IKZF3 Rabbit pAb
Cat No.: APA4786
Size:
Product Name: | IKZF3 Rabbit pAb |
Cat No.: | APA4786 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human IKZF3 |
calculated molecular weight: | 58 kDa |
observed molecular weight: | 58 kDa |
genbank accession number: | Q9UKT9 |
gene id (ncbi): | 22806 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | AIO; AIOLOS; ZNFN1A3 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012] |