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Hemoglobin subunit alpha Rabbit pAb

Cat No.: APA4759
Size:
Product Name: Hemoglobin subunit alpha Rabbit pAb
Cat No.: APA4759
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:20-1:100
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Hemoglobin subunit alpha
calculated molecular weight: 15 kDa
observed molecular weight: 15 kDa
genbank accession number: P69905
gene id (ncbi): 3039
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HBH; HBA-T3
category: Primary Ab
concentration: 0.5mg/ml
background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5--- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3--. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5-- untranslated regions and the introns, but they differ significantly over the 3-- untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]