Hemoglobin subunit alpha Rabbit pAb
Cat No.: APA4759
| Product Name: | Hemoglobin subunit alpha Rabbit pAb |
| Cat No.: | APA4759 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20-1:100 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Hemoglobin subunit alpha |
| calculated molecular weight: | 15 kDa |
| observed molecular weight: | 15 kDa |
| genbank accession number: | P69905 |
| gene id (ncbi): | 3039 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HBH; HBA-T3 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5--- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3--. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5-- untranslated regions and the introns, but they differ significantly over the 3-- untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008] |
