HIP2 Rabbit pAb
Cat No.: APA4733
Size：
| Product Name: | HIP2 Rabbit pAb |
| Cat No.: | APA4733 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000 IHC: 1:50-1:200 ICC/IF: 1:50 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human HIP2 |
| calculated molecular weight: | 22 kDa |
| observed molecular weight: | 22 kDa |
| genbank accession number: | P61086 |
| gene id (ncbi): | 3093 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | LIG; HIP2; HYPG; UBC1; E2-25K |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington--s disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |