GRAF Rabbit pAb
Cat No.: APA4718
Size：
| Product Name: | GRAF Rabbit pAb |
| Cat No.: | APA4718 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 FC: 1:20-1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human GRAF |
| calculated molecular weight: | 92 kDa |
| observed molecular weight: | 92 kDa |
| genbank accession number: | Q9UNA1 |
| gene id (ncbi): | 23092 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | GRAF; GRAF1; OPHN1L; OPHN1L1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017] |