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beta 2 Adrenergic Receptor Rabbit pAb

Cat No.: APA4691
Size:
Product Name: beta 2 Adrenergic Receptor Rabbit pAb
Cat No.: APA4691
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human beta 2 Adrenergic Receptor
calculated molecular weight: 47 kDa
observed molecular weight: 70 kDa
genbank accession number: P07550
gene id (ncbi): 154
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: BAR; B2AR; ADRBR; ADRB2R; BETA2AR
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]