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CD11c Rabbit pAb

Cat No.: APA4649
Size:
Product Name: CD11c Rabbit pAb
Cat No.: APA4649
source: Rabbit
reactivity: Human
applications: WB,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
ICC/IF: 1:50-1:200
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human CD11c
calculated molecular weight: 128 kDa
observed molecular weight: 150 kDa
genbank accession number: P20702
gene id (ncbi): 3687
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CD11C; SLEB6
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]