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RAIDD Rabbit pAb

Cat No.: APA4610
Size:
Product Name: RAIDD Rabbit pAb
Cat No.: APA4610
source: Rabbit
reactivity: Human, Rat
applications: WB,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:2000
ICC/IF: 1:20-1:50
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human RAIDD
calculated molecular weight: 23 kDa
observed molecular weight: 23 kDa
genbank accession number: P78560
gene id (ncbi): 8738
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: MRT34; RAIDD
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]