Caspase-2 Rabbit pAb
Cat No.: APA4602
Size:
Product Name: | Caspase-2 Rabbit pAb |
Cat No.: | APA4602 |
source: | Rabbit |
reactivity: | Human |
applications: | WB |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Caspase-2 |
calculated molecular weight: | 51 kDa |
observed molecular weight: | 51 kDa |
genbank accession number: | P42575 |
gene id (ncbi): | 835 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer--s disease, Huntington--s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |