NQO1 Rabbit pAb
Cat No.: APA4591
Size:
Product Name: | NQO1 Rabbit pAb |
Cat No.: | APA4591 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human NQO1 |
calculated molecular weight: | 31 kDa |
observed molecular weight: | 31 kDa |
genbank accession number: | P15559 |
gene id (ncbi): | 1728 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | DTD; QR1; DHQU; DIA4; NMOR1; NMORI |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein--s enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer--s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |