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HMGA2 Rabbit pAb

Cat No.: APA4564
Size:
Product Name: HMGA2 Rabbit pAb
Cat No.: APA4564
source: Rabbit
reactivity: Human
applications: IHC,ICC/IF
clonality: Polyclonal
recommended dilution: IHC: 1:200
ICC/IF: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human HMGA2
calculated molecular weight: 12 kDa
observed molecular weight:
genbank accession number: P52926
gene id (ncbi): 8091
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: BABL; LIPO; HMGIC; HMGI-C; STQTL9
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]