CCR7 Rabbit pAb
Cat No.: APA4561
Size：
| Product Name: | CCR7 Rabbit pAb |
| Cat No.: | APA4561 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human CCR7 |
| calculated molecular weight: | 43 kDa |
| observed molecular weight: | 43 kDa |
| genbank accession number: | P32248 |
| gene id (ncbi): | 1236 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |