TRPM8 Rabbit pAb
Cat No.: APA4544
Size：
| Product Name: | TRPM8 Rabbit pAb |
| Cat No.: | APA4544 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 ICC/IF: 1:50-1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human TRPM8 |
| calculated molecular weight: | 128 kDa |
| observed molecular weight: | 128 kDa |
| genbank accession number: | Q7Z2W7 |
| gene id (ncbi): | 79054 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | TRPP8; LTRPC6; trp-p8; LTrpC-6 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. |