NOXA2/p67phox Rabbit pAb
Cat No.: APA4541
Size:
Product Name: | NOXA2/p67phox Rabbit pAb |
Cat No.: | APA4541 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:2000 IHC: 1:50-1:200 ICC/IF: 1:50-1:100 IP: 1:20-1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human NOXA2/p67phox |
calculated molecular weight: | 60 kDa |
observed molecular weight: | 60 kDa |
genbank accession number: | P19878 |
gene id (ncbi): | 4688 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | NCF-2; NOXA2; P67PHOX; P67-PHOX |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010] |