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Fibrinopeptide B Rabbit pAb

Cat No.: APA4495
Size:
Product Name: Fibrinopeptide B Rabbit pAb
Cat No.: APA4495
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:20-1:50
ICC/IF: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Fibrinopeptide B
calculated molecular weight: 56 kDa
observed molecular weight: 56 kDa
genbank accession number: P02675
gene id (ncbi): 2244
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HEL-S-78p
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]