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alpha 1 Spectrin Rabbit pAb

Cat No.: APA4480
Size:
Product Name: alpha 1 Spectrin Rabbit pAb
Cat No.: APA4480
source: Rabbit
reactivity: Human
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:50-1:200
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human alpha 1 Spectrin
calculated molecular weight: 280 kDa
observed molecular weight: 280 kDa
genbank accession number: P02549
gene id (ncbi): 6708
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: EL2; HPP; HS3; SPH3; SPTA
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3. [provided by RefSeq, Aug 2017]