HARS Rabbit pAb
Cat No.: APA4478
Size：
| Product Name: | HARS Rabbit pAb |
| Cat No.: | APA4478 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 IP: 1:20-1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human HARS |
| calculated molecular weight: | 57 kDa |
| observed molecular weight: | 57 kDa |
| genbank accession number: | P12081 |
| gene id (ncbi): | 3035 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HRS; CMT2W; USH3B |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |