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GABA A Receptor alpha 1 Rabbit pAb

Cat No.: APA4476
Size:
Product Name: GABA A Receptor alpha 1 Rabbit pAb
Cat No.: APA4476
source: Rabbit
reactivity: Human
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:20-1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human GABA A Receptor alpha 1
calculated molecular weight: 52 kDa
observed molecular weight: 52 kDa
genbank accession number: P14867
gene id (ncbi): 2554
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: EJM; ECA4; EJM5; EIEE19
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]