PDZK1 Rabbit pAb
Cat No.: APA4472
Size：
| Product Name: | PDZK1 Rabbit pAb |
| Cat No.: | APA4472 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human PDZK1 |
| calculated molecular weight: | 57 kDa |
| observed molecular weight: | 70 kDa |
| genbank accession number: | Q5T2W1 |
| gene id (ncbi): | 5174 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CAP70; CLAMP; PDZD1; NHERF3; NHERF-3 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |