MSH3 Rabbit pAb
Cat No.: APA4456
Size：
| Product Name: | MSH3 Rabbit pAb |
| Cat No.: | APA4456 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:50-1:200 ICC/IF: 1:50-1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human MSH3 |
| calculated molecular weight: | 127 kDa |
| observed molecular weight: | |
| genbank accession number: | P20585 |
| gene id (ncbi): | 4437 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DUP; FAP4; MRP1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011] |