TORC1 Rabbit pAb
Cat No.: APA4452
Size：
| Product Name: | TORC1 Rabbit pAb |
| Cat No.: | APA4452 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human TORC1 |
| calculated molecular weight: | 67 kDa |
| observed molecular weight: | 78 kDa |
| genbank accession number: | Q6UUV9 |
| gene id (ncbi): | 23373 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | MECT1; TORC1; TORC-1; WAMTP1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 --Ser-133-- phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. |