Osteoprotegerin Rabbit pAb
Cat No.: APA4451
Size：
| Product Name: | Osteoprotegerin Rabbit pAb |
| Cat No.: | APA4451 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:20-1:100 ICC/IF: 1:20-1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Osteoprotegerin |
| calculated molecular weight: | 46 kDa |
| observed molecular weight: | |
| genbank accession number: | O00300 |
| gene id (ncbi): | 4982 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | OPG; TR1; OCIF; PDB5 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008] |