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Ionotropic Glutamate receptor 4 Rabbit pAb

Cat No.: APA4413
Size:
Product Name: Ionotropic Glutamate receptor 4 Rabbit pAb
Cat No.: APA4413
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Ionotropic Glutamate receptor 4
calculated molecular weight: 101 kDa
observed molecular weight: 101 kDa
genbank accession number: P48058
gene id (ncbi): 2893
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: GLUR4; GLURD; GluA4; GLUR4C
category: Primary Ab
concentration: 0.5mg/ml
background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]