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GRB2 Rabbit pAb

Cat No.: APA4411
Size:
Product Name: GRB2 Rabbit pAb
Cat No.: APA4411
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000
IHC: 1:50
ICC/IF: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human GRB2
calculated molecular weight: 25 kDa
observed molecular weight: 25 kDa
genbank accession number: P62993
gene id (ncbi): 2885
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]