70 kD Neurofilament Light Rabbit pAb
Cat No.: APA4405
Size：
| Product Name: | 70 kD Neurofilament Light Rabbit pAb |
| Cat No.: | APA4405 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:2000 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human 70 kD Neurofilament Light |
| calculated molecular weight: | 62 kDa |
| observed molecular weight: | 70 kDa |
| genbank accession number: | P07196 |
| gene id (ncbi): | 4747 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008] |