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PIP5KI gamma Rabbit pAb

Cat No.: APA4404
Size:
Product Name: PIP5KI gamma Rabbit pAb
Cat No.: APA4404
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IP: 1:20-1:50
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse PIP5KI gamma
calculated molecular weight: 73 kDa
observed molecular weight: 90,87 kDa
genbank accession number: O70161
gene id (ncbi): 18717
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AI115456; AI835305; Pip5kIgamma
category: Primary Ab
concentration: 0.5mg/ml
background: Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as vesicle mediated transport, cell adhesion, cell polarization and cell migration. Together with PIP5K1A is required for phagocytosis, but they regulate different types of actin remodeling at sequential steps.